Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001266 | 0.90 | MAOB (0.38) | MAOBADRA2AHPGDALDH1A1BRD4 | |
| SCHEMBL7992032 | 0.88 | KDM4E (0.43) | MAOBHPGDALDH1A1BRD4MEN1 | |
| SCHEMBL8004054 | 0.88 | MAOB (0.37) | MAOBADRA2AHPGDALDH1A1BRD4 | |
| SCHEMBL7998991 | 0.86 | ADRA2A (0.38) | MAOBADRA2AHPGDALDH1A1BRD4 | |
| SCHEMBL7998972 | 0.85 | MAOB (0.41) | MAOBCASRADRA2AHPGDALDH1A1 | |
| SCHEMBL8002092 | 0.85 | AR (0.34) | CASRMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL8004876 | 0.83 | MEN1 (0.44) | MAOBCASRADRA2AHPGDALDH1A1 | |
| SCHEMBL8002068 | 0.83 | ADRA2A (0.40) | MAOBCASRADRA2AHPGDALDH1A1 | |
| SCHEMBL7999664 | 0.83 | MAOB (0.36) | MAOBCASRADRA2AHPGDALDH1A1 | |
| SCHEMBL8001061 | 0.81 | ADRA2A (0.41) | MAOBCASRADRA2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |