Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474606 | 0.93 | ADRA2A (0.35) | MAOBCASRMEN1KMT2APOLB | |
| SCHEMBL8001337 | 0.93 | ALOX15 (0.38) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8001330 | 0.93 | ALOX15 (0.38) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7988986 | 0.90 | MAOB (0.38) | MAOBMEN1KMT2ACYP1A2POLB | |
| SCHEMBL8004050 | 0.88 | MAOB (0.36) | MAOBMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8074644 | 0.88 | KDM4E (0.41) | MAOBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7998987 | 0.86 | ADRA2A (0.38) | MAOBMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7998972 | 0.85 | MAOB (0.41) | MAOBCASRMEN1KMT2ACYP1A2 | |
| SCHEMBL8002087 | 0.84 | TP53 (0.33) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8002068 | 0.84 | ADRA2A (0.40) | MAOBCASRMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |