Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 11/20 | 0.74 |
| ▸ | CDK2 | P24941 | 8/20 | 0.74 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.74 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.74 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.74 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.74 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.74 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Olomoucine SCHEMBL135056 | 0.85 | CDK1 (1.00) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL1216905 | 0.82 | CDK1 (1.00) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL14182620 | 0.79 | CDK1 (0.87) | CDK1CDK2CDK5TDP1CCNB2 | |
| Bohemine SCHEMBL29572816 | 0.76 | CDK1 (1.00) | CDK1CDK2CDK5TDP1CCNB2 | |
| Bohemine SCHEMBL1443403 | 0.76 | CDK1 (1.00) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL7112489 | 0.75 | CDK1 (0.94) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL7113555 | 0.75 | CDK1 (0.92) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL13252976 | 0.74 | CDK1 (0.81) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL7099130 | 0.74 | CDK1 (0.69) | CDK1CDK2CDK5TDP1CCNB2 | |
| SCHEMBL7173102 | 0.74 | CDK1 (0.78) | CDK1CDK2CDK5TDP1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033657-A1 | METHOD TO IDENTIFY REGULATORS OF CDK ACTIVITY | CROPDESIGN N.V. (BE) | 2000-06-15 | — | — | WO | claimed |
| WO-2000033657-A1 | METHOD TO IDENTIFY REGULATORS OF CDK ACTIVITY | CROPDESIGN N.V. (BE) | 2000-06-15 | — | — | WO | disclosed |