Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.58 |
| ▸ | HPN | P05981 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986780 | 0.95 | F10 (0.62) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7986762 | 0.94 | F10 (0.55) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7986943 | 0.90 | F10 (0.56) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7986749 | 0.90 | F10 (0.56) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7999935 | 0.89 | F10 (0.56) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7999904 | 0.89 | F10 (0.53) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7986772 | 0.88 | F10 (0.57) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL10841960 | 0.85 | APP (0.62) | APPHRH3MCHR1PRMT5WDR77 | |
| SCHEMBL8000015 | 0.85 | F10 (0.53) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7996092 | 0.84 | F10 (0.58) | F10HPNPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |