Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.77 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TDP2 | O95551 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | GALK1 | P51570 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114187 | 0.87 | ALDH1A1 (1.00) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL7149363 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL13847076 | 0.78 | MAPT (0.62) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL4008226 | 0.78 | NPSR1 (0.71) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL14307227 | 0.77 | MAPT (0.53) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL7108506 | 0.74 | CHRM2 (0.49) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL3971547 | 0.74 | CHRM2 (0.49) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL14565662 | 0.71 | NPSR1 (0.61) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL11441957 | 0.69 | LMNA (0.45) | ALDH1A1MAPTNPSR1L3MBTL1HTT | |
| SCHEMBL11435300 | 0.67 | MAPT (0.50) | ALDH1A1MAPTNPSR1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153645-A | FOR INHIBITING GROWTH OF MICROORGANISMS; INHIBITOR OF AMINOACYL-TRNA SYNTHETASE | CUBIST PHARMACEUTICALS, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| WO-2000017206-A1 | TETRACYCLIC HETEROCYCLES AS ANTIMICROBIAL AGENTS | CUBIST PHARMACEUTICALS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |