Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992766 | 0.91 | ALDH1A1 (0.50) | ALDH1A1POLBKDM4ESMN1; SMN2TP53BP1 | |
| SCHEMBL7999667 | 0.86 | ALDH1A1 (0.48) | ALDH1A1POLBKDM4ESMN1; SMN2TP53BP1 | |
| SCHEMBL7995797 | 0.79 | ALDH1A1 (0.52) | ALDH1A1POLBKDM4ESMN1; SMN2TP53BP1 | |
| SCHEMBL2859647 | 0.75 | ALDH1A1 (0.72) | ALDH1A1POLBKDM4ESMN1; SMN2TP53BP1 | |
| SCHEMBL15933244 | 0.75 | ALDH1A1 (0.56) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL7992778 | 0.74 | KMT2A (0.57) | ALDH1A1POLBTP53BP1NPC1ABCB1 | |
| SCHEMBL3876454 | 0.72 | CES2 (0.65) | ALDH1A1POLBNPSR1GAA | |
| SCHEMBL20870672 | 0.69 | CES2 (0.65) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL27970190 | 0.69 | POLB (0.74) | ALDH1A1POLBTP53BP1HDAC3HDAC1 | |
| SCHEMBL6360091 | 0.69 | POLB (1.00) | ALDH1A1POLBSMN1; SMN2TP53BP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046152-A1 | HERBICIDAL DIACYL DERIVATIVES OF PROPYLENE DIAMINE | MONSANTO TECHNOLOGY LLC (US) | 2001-06-28 | — | — | WO | disclosed |