Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384303 | 0.89 | POLB (0.56) | L3MBTL1KMT2AHTTLMNATSHR | |
| SCHEMBL27332955 | 0.80 | L3MBTL1 (0.61) | L3MBTL1KMT2AKDM4EHTTLMNA | |
| SCHEMBL3119295 | 0.77 | TSHR (0.69) | L3MBTL1KMT2AKDM4EHTTLMNA | |
| SCHEMBL13315024 | 0.71 | L3MBTL1 (0.56) | L3MBTL1KMT2AKDM4EHTTLMNA | |
| SCHEMBL1343383 | 0.71 | KMT2A (0.61) | L3MBTL1KMT2AHTTLMNAPOLB | |
| SCHEMBL27783476 | 0.69 | POLB (0.42) | L3MBTL1KMT2AKDM4EHTTLMNA | |
| SCHEMBL12569137 | 0.68 | TSHR (0.68) | L3MBTL1KMT2AHTTLMNATSHR | |
| SCHEMBL5743015 | 0.67 | KMT2A (0.56) | L3MBTL1KMT2AHTTLMNAPOLB | |
| SCHEMBL4344258 | 0.67 | TSHR (0.57) | L3MBTL1KMT2AKDM4ELMNATSHR | |
| SCHEMBL14518853 | 0.67 | DPP4 (0.47) | L3MBTL1KMT2AKDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |