Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996221 | 0.90 | PLA2G2A (0.42) | ALDH1A1HCRTR1HCRTR2PLA2G2AFBP1 | |
| SCHEMBL7999778 | 0.86 | SLC2A1 (0.43) | ALDH1A1HCRTR1HCRTR2PLA2G2AFBP1 | |
| SCHEMBL7999728 | 0.86 | PLA2G2A (0.42) | ALDH1A1HCRTR1HCRTR2PLA2G2AFBP1 | |
| SCHEMBL7999722 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HCRTR1HCRTR2PLA2G2AKMT2A | |
| SCHEMBL7997813 | 0.83 | HCRTR1 (0.44) | ALDH1A1POLBHCRTR1HCRTR2PLA2G2A | |
| SCHEMBL8003297 | 0.83 | SLC2A1 (0.41) | ALDH1A1HCRTR1HCRTR2PLA2G2AFBP1 | |
| SCHEMBL7073968 | 0.80 | MAPT (0.50) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL7996342 | 0.79 | HCRTR1 (0.47) | ALDH1A1POLBHCRTR1HCRTR2PLA2G2A | |
| SCHEMBL7997762 | 0.78 | TSHR (0.55) | ALDH1A1HCRTR1HCRTR2PLA2G2AMCHR1 | |
| SCHEMBL7997810 | 0.77 | F10 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |