Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582804 | 0.80 | LMNA (0.46) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| SCHEMBL3919570 | 0.79 | TSHR (0.44) | LMNATSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1563242 | 0.77 | CA2 (0.61) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| SCHEMBL93796 | 0.77 | CA2 (0.61) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| SCHEMBL20080951 | 0.76 | LMNA (0.46) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28149524 | 0.75 | CA2 (0.59) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| SCHEMBL1589664 | 0.75 | CA2 (0.59) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27699249 | 0.75 | CA2 (0.59) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| SCHEMBL14862486 | 0.75 | CA2 (0.59) | LMNATSHRALDH1A1NT5ESMN1; SMN2 | |
| SCHEMBL1589452 | 0.75 | CA2 (0.59) | LMNATSHRALDH1A1NT5ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |