Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113863 | 0.83 | — | — | |
| Methyl Carbamate SCHEMBL28857887 | 0.77 | LMNA (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL3262366 | 0.77 | LMNA (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL29728569 | 0.72 | LMNA (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL16244135 | 0.71 | — | — | |
| SCHEMBL30036014 | 0.69 | ALDH1A1 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL11981899 | 0.69 | RNPEP (0.35) | CYP2C9MAPTMETAP2METAP1 | |
| SCHEMBL29194221 | 0.68 | LMNA (0.48) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL28530549 | 0.68 | LMNA (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL28530548 | 0.68 | LMNA (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732944-A4 | LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION | GEN HOSPITAL CORP (US) | 2000-06-07 | — | — | EP | disclosed |
| EP-0732944-A1 | LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION | THE GENERAL HOSPITAL CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995011045-A1 | LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION | THE GENERAL HOSPITAL CORPORATION (US) | 1995-04-27 | — | — | WO | disclosed |