Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991130 | 0.91 | PLAU (1.00) | PLAUALDH1A1CA12CA1CA2 | |
| SCHEMBL30334777 | 0.91 | PLAU (1.00) | PLAUALDH1A1CA12CA1CA2 | |
| SCHEMBL588930 | 0.91 | PLAU (1.00) | PLAUALDH1A1CA12CA1CA2 | |
| SCHEMBL30566787 | 0.89 | PLAU (0.96) | PLAUALDH1A1TDP1CTDSP1ESR1 | |
| 1-Naphthol SCHEMBL9293009 | 0.87 | ALDH1A1 (0.63) | PLAUALDH1A1CA12CA1CA2 | |
| 4-Aminophenol SCHEMBL5573958 | 0.87 | PLAU (0.85) | PLAUALDH1A1CA12CA1CA2 | |
| 3-Aminophenol SCHEMBL8000117 | 0.79 | ALDH1A1 (0.61) | PLAUALDH1A1CA12CA1CA2 | |
| SCHEMBL15451 | 0.78 | HSD17B1 (0.70) | PLAUESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL29364213 | 0.78 | HSD17B1 (0.70) | PLAUESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL29738652 | 0.78 | HSD17B1 (0.70) | PLAUESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |