Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.49 |
| ▸ | FNTB | P49356 | 2/20 | 0.49 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.48 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000420 | 1.00 | MEN1 (0.53) | MEN1KMT2AALDH1A1L3MBTL1FNTA | |
| Trifluoroacetic Acid SCHEMBL7997330 | 0.93 | MEN1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1FNTA | |
| Trifluoroacetic Acid SCHEMBL7997333 | 0.93 | MEN1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1FNTA | |
| SCHEMBL9471092 | 0.78 | MEN1 (0.64) | MEN1KMT2AALDH1A1L3MBTL1SLC10A2 | |
| SCHEMBL7997160 | 0.78 | F2R (0.48) | MEN1KMT2AALDH1A1FNTAFNTB | |
| SCHEMBL7997161 | 0.78 | F2R (0.48) | MEN1KMT2AALDH1A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8868826 | 0.77 | F2R (0.47) | MEN1KMT2AALDH1A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8868833 | 0.77 | F2R (0.47) | MEN1KMT2AALDH1A1FNTAFNTB | |
| SCHEMBL12812751 | 0.76 | MEN1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1SLC10A2 | |
| SCHEMBL27134479 | 0.75 | RXFP1 (0.67) | MEN1KMT2AALDH1A1L3MBTL1SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | claimed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5631280-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |