⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921726 | 1.00 | — | — | |
| SCHEMBL4921734 | 1.00 | — | — | |
| SCHEMBL1071659 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL1071656 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL16504 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL25405174 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL16505 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL25405178 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL16503 | 0.75 | HCAR2 (0.40) | — | |
| SCHEMBL37099 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699925-A | ANTIINFLAMMATORY AGENTS, ANALGESICS AND-OR ANTIPYRETICS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1987-10-13 | — | — | US | claimed |
| EP-0103265-B1 | BIPHENYLYLPROPIONIC ACID DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-12-03 | — | — | EP | claimed |
| US-4613505-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | THE GREEN CROSS CORPORATION (JP) | 1986-09-23 | — | — | US | claimed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | claimed |
| JP-60028957-A | — | — | None | — | — | JP | disclosed |
| US-6159654-A | Negative photosensitive polymer composition of a thermosetting polymer precursor curable by cyclodehydration upon heating | KABUSHIKI KAISHA TOSHIBA (JP) | 2000-12-12 | — | — | US | disclosed |
| US-5171566-A | Applying fat emulsion containing phospholipid, soybean oil, flurbiprofen ester | THE GREEN CROSS CORPORATION (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0253472-B1 | OPHTHALMIC FLURBIPROFEN PREPARATION | GREEN CROSS CORPORATION (JP) | 1992-05-06 | — | — | EP | disclosed |
| EP-0129435-B1 | ESTER OF FLURBIPROFEN AND EMULSION CONTAINING THE SAME | GREEN CROSS CORPORATION (JP) | 1988-11-17 | — | — | EP | disclosed |
| EP-0253472-A1 | Ophthalmic flurbiprofen preparation | GREEN CROSS CORPORATION (JP) | 1988-01-20 | — | — | EP | disclosed |
| US-4699925-A | ANTIINFLAMMATORY AGENTS, ANALGESICS AND-OR ANTIPYRETICS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0103265-B1 | BIPHENYLYLPROPIONIC ACID DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-12-03 | — | — | EP | disclosed |
| US-4613505-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | THE GREEN CROSS CORPORATION (JP) | 1986-09-23 | — | — | US | disclosed |
| JP-S6028957-A | ESTER DERIVATIVES OF INDOLYLACETIC ACID AND PHENYLACETIC ACID AND THEIR PRODUCTION | KAKEN PHARMACEUT CO LTD | 1985-02-14 | — | — | JP | disclosed |
| EP-0129435-A2 | Ester of flurbiprofen and emulsion containing the same | GREEN CROSS CORPORATION (JP) | 1984-12-27 | — | — | EP | disclosed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4385177-A | Cephalosporins having a carbamoylalkoxyiminoarylacetamido group at 7-position | GLAXO LABORATORIES, LTD. (GB) | 1983-05-24 | — | — | US | disclosed |
| US-4208517-A | Caphalosporin compounds having at position-7 an α-etherified hydroxyiminoarylacetamido group | GLAXO OPERATIONS UK LIMITED (GB) | 1980-06-17 | — | — | US | disclosed |
| US-4103084-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-07-25 | — | — | US | disclosed |
| US-4007174-A | Cephalosporin compounds | GLAXO LABORATORIES LIMITED (EN) | 1977-02-08 | — | — | US | disclosed |