Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867193 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL11661313 | 0.85 | MAPT (0.59) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL1903659 | 0.84 | CYP4F2 (0.58) | SMN1; SMN2CYP4A11CYP4F2MAPTRAB9A | |
| SCHEMBL14614457 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL8867553 | 0.83 | CYP4F2 (0.59) | SMN1; SMN2CYP4A11CYP4F2MAPTRAB9A | |
| SCHEMBL2244813 | 0.83 | CYP17A1 (0.58) | CYP4A11CYP4F2 | |
| SCHEMBL1022686 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL12582054 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL2088667 | 0.82 | POLB (0.64) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL8867136 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP4A11CYP4F2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423758-A | Adenosine receptor binding compounds | 尼康治疗公司 | 2021-02-26 | — | — | CN | disclosed |
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |
| EP-0991632-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | Astra Aktiebolag (SE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057941-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1998-12-23 | — | — | WO | disclosed |
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |