Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866630 | 0.91 | RAB9A (0.63) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL13387551 | 0.90 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL8867130 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL1903659 | 0.87 | CYP4F2 (0.58) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7562459 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL1021995 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL7472487 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9211588 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL8000487 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL27110837 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |