Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 3/20 | 0.86 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.86 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5189418 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL1806395 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL3800182 | 1.00 | — | — | |
| Sulfuric Acid SCHEMBL18986095 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL1921997 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL8506703 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL19741763 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL16013217 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL2323392 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL16105744 | 1.00 | CA5A (0.86) | CA5ACA5BTSHRCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114428-A | COMPRISING SMELT OF PARTICLE SIZE OF 0.0005MM AS A FILLER, FOAMING AGENT AND OR STABILIZER; SMELT IS A BY-PRODUCT OF THE PULP AND PAPER INDUCTRY AND COMPRISES INORGANIC SALTS OF SODIUM; POLLUTION CONTROL | MORTILE INDUSTRIES LTD. (CA) | 2000-09-05 | — | — | US | claimed |
| EP-0970146-A1 | COMPOSITIONS OF THERMOPLASTIC POLYMER AND SMELT | THE DOW CHEMICAL COMPANY (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1998042779-A1 | COMPOSITIONS OF THERMOPLASTIC POLYMER AND SMELT | THE DOW CHEMICAL COMPANY (US) | 1998-10-01 | — | — | WO | claimed |
| US-6281276-B1 | POLYVINYL CHLORIDE | THE DOW CHEMICAL COMPANY | 2001-08-28 | — | — | US | disclosed |
| US-6114428-A | COMPRISING SMELT OF PARTICLE SIZE OF 0.0005MM AS A FILLER, FOAMING AGENT AND OR STABILIZER; SMELT IS A BY-PRODUCT OF THE PULP AND PAPER INDUCTRY AND COMPRISES INORGANIC SALTS OF SODIUM; POLLUTION CONTROL | MORTILE INDUSTRIES LTD. (CA) | 2000-09-05 | — | — | US | disclosed |
| EP-0970146-A1 | COMPOSITIONS OF THERMOPLASTIC POLYMER AND SMELT | THE DOW CHEMICAL COMPANY (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998042779-A1 | COMPOSITIONS OF THERMOPLASTIC POLYMER AND SMELT | THE DOW CHEMICAL COMPANY (US) | 1998-10-01 | — | — | WO | disclosed |