Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.75 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501329 | 0.87 | CA2 (0.58) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL3402693 | 0.86 | PTGS2 (0.77) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL6921591 | 0.86 | HTT (0.55) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL17949734 | 0.84 | PTGS2 (0.75) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL30483538 | 0.84 | HTT (0.76) | PTGS2CA1CA2CA9TP53 | |
| SCHEMBL13754541 | 0.82 | PTGS2 (0.71) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL3406088 | 0.82 | PTGS2 (0.71) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL13832881 | 0.81 | PTGS2 (0.69) | PTGS2CA1CA2CA9TP53 | |
| SCHEMBL3402296 | 0.80 | TP53 (0.75) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL30153810 | 0.76 | MAPT (0.49) | PTGS2TP53HTTMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642837-B | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2023-03-21 | — | — | CN | disclosed |
| WO-2009115486-A1 | TRIAZOLE AMIDE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |