Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15801114 | 0.87 | MAPT (0.71) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL17669252 | 0.87 | MAPT (0.71) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL20456232 | 0.84 | MAPT (0.52) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL9531913 | 0.84 | NPC1 (0.68) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL336009 | 0.80 | NPC1 (0.65) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL15156349 | 0.80 | MAPT (0.62) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL909633 | 0.80 | MAPT (0.62) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11207169 | 0.79 | MAPT (0.61) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1372140 | 0.79 | MAPT (0.66) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL26356999 | 0.79 | MAPT (0.61) | MAPTKMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070726-A1 | AMINOPHENYL PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |