Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LAP3 | P28838 | 2/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.53 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4394524 | 0.99 | TDP1 (0.53) | TDP1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL8001760 | 0.97 | TDP1 (0.57) | TDP1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5718258 | 0.96 | TDP1 (0.60) | TDP1LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL17596474 | 0.95 | TDP1 (0.58) | TDP1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL10085519 | 0.94 | LAP3 (0.56) | TDP1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL21554929 | 0.94 | LAP3 (0.56) | TDP1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL20027600 | 0.94 | LAP3 (0.56) | TDP1LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL3841624 | 0.93 | LAP3 (0.54) | TDP1LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL288950 | 0.93 | LAP3 (0.54) | TDP1LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL289721 | 0.93 | LAP3 (0.54) | TDP1LAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117870-A | USEFUL AS THERAPEUTIC DRUG OR PREVENTIVE DRUG OF ARTHRITIS AND RHEUMATISM DUE TO INCREASE OF BONE RESORPTION IN ADDITION TO BONE DISEASES SUCH AS OSTEOPOROSIS, HYPERCALCEMIA, AND PAGET'S DISEASE | FUJIREBIO KABUSHIKI KAISHA (JP) | 2000-09-12 | — | — | US | disclosed |