Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006518 | 0.83 | IDO1 (1.00) | IDO1HPGDALDH1A1POLBGPR35 | |
| SCHEMBL197490 | 0.83 | IDO1 (1.00) | IDO1HPGDALDH1A1POLBGPR35 | |
| SCHEMBL29475880 | 0.83 | IDO1 (1.00) | IDO1HPGDALDH1A1POLBGPR35 | |
| SCHEMBL8003432 | 0.82 | IDO1 (0.70) | IDO1LDHAHPGDALDH1A1LMNA | |
| SCHEMBL8003535 | 0.80 | PTPN22 (0.60) | IDO1LDHAHPGDALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL588687 | 0.80 | PTPN22 (0.60) | IDO1LDHAHPGDALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL29399146 | 0.80 | PTPN22 (0.60) | IDO1LDHAHPGDALDH1A1CYP2D6 | |
| SCHEMBL144495 | 0.80 | PTPN22 (0.60) | IDO1LDHAHPGDALDH1A1CYP2D6 | |
| SCHEMBL30168079 | 0.80 | PTPN22 (0.60) | IDO1LDHAHPGDALDH1A1CYP2D6 | |
| SCHEMBL8003575 | 0.79 | IDO1 (0.66) | IDO1LDHAHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |