Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL588687 | 1.00 | PTPN22 (0.60) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| Hydrochloric Acid SCHEMBL29399146 | 1.00 | PTPN22 (0.60) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL144495 | 1.00 | PTPN22 (0.60) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL30168079 | 1.00 | PTPN22 (0.60) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| Hydrogen Sulfide SCHEMBL28776700 | 0.98 | PTPN22 (0.58) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| Methane SCHEMBL29209224 | 0.98 | PTPN22 (0.58) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| Sulfamide SCHEMBL3573443 | 0.90 | PTPN22 (0.55) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| Sulfuric Acid SCHEMBL7879258 | 0.90 | PTPN22 (0.50) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL29484713 | 0.89 | HPRT1 (0.59) | PTPN22HSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL2466022 | 0.84 | ALDH1A1 (0.52) | PTPN22HSD17B10ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |