SCHEMBL197490

SCHEMBL197490

Nc1cc2ccccc2cc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 1.00
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
HPGD P15428 2/20 0.53
GFER P55789 2/20 0.52
KMT2A Q03164 2/20 0.52
RXFP1 Q9HBX9 1/20 0.52
MAPT P10636 3/20 0.52
NGLY1 Q96IV0 1/20 0.52
POLB P06746 2/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
THRB P10828 1/20 0.50
PKM P14618 1/20 0.50
APEX1 P27695 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
MCL1 Q07820 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PTPN1 P18031 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8006518 1.00 IDO1 (1.00) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL29475880 1.00 IDO1 (1.00) IDO1KDM4EALDH1A1HPGDGFER
Questiomycin B SCHEMBL8006530 0.89 IDO1 (0.79) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL7592067 0.86 IDO1 (0.74) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL15133540 0.86 IDO1 (0.75) IDO1KDM4EALDH1A1HPGDGFER
3-Aminophenol SCHEMBL7991041 0.85 IDO1 (0.72) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL22328876 0.84 IDO1 (0.71) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL14503721 0.84 IDO1 (0.71) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL69178 0.84 IDO1 (0.71) IDO1KDM4EALDH1A1HPGDGFER
SCHEMBL29373760 0.84 IDO1 (0.71) IDO1KDM4EALDH1A1HPGDGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
CN-119781246-A Photosensitive polyimide resin composition, cured film, and preparation method and application thereof 吉林奥来德光电材料股份有限公司 2025-04-08 CN claimed
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
CN-118637984-A Synthesis method of (4-chloro-naphthalene-2-yl) -methanol 埃法姆(常州)生命科学技术有限公司 2024-09-13 CN claimed
CN-117416983-A Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method 中国科学院青海盐湖研究所 2024-01-19 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
WO-2023014909-A1 AMPHIPHILIC PEPTIDES FOR NUCLEIC ACID AND PROTEIN DELIVERY AJK Biopharmaceutical, LLC (US) 2023-02-09 WO claimed
US-20230000999-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY PARANG KEYKAVOUS (US) 2023-01-05 US claimed
CN-115244067-A Synthetic antimicrobial peptides AJK生物制药有限责任公司 2022-10-25 CN claimed
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK BIOPHARMACEUTICAL LLC (US) 2022-09-15 US claimed
EP-0820759-A2 Compositions for dyeing keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-01-28 EP claimed
EP-0515379-A4 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INC (US) 1994-09-14 EP claimed
EP-0515379-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1992-12-02 EP claimed
US-5094740-A TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED, INC. (US) 1992-03-10 US claimed
WO-1991012275-A1 TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
WO-1991012276-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
US-4996339-A Colorless ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-26 US claimed
US-4855208-A Toner for developing electrostatic latent images ORIENT CHEMICAL INDUSTRIES LTD. (JP) 1989-08-08 US claimed
EP-0210751-A2 Halogen-containing rubbers and their manufacture MARINE MAGNESIUM COMPANY (US) 1987-02-04 EP claimed
US-4632954-A WITH AMINOCARBOXY COMPOUNDS CALGON CORPORATION (US) 1986-12-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000999-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY ARGLU1, SLC7A11, PNISR IDO1 416/4885KDM4E 4432/4885ALDH1A1 4266/4885
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES VIP, HM13, NGLY1 IDO1 1485/4885KDM4E 3892/4885ALDH1A1 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.