SCHEMBL8002126

SCHEMBL8002126

NC(=O)C=Cc1ccccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.62
HDAC8 Q9BY41 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
GSR P00390 1/20 0.62
MAPT P10636 7/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
MAOB P27338 3/20 0.57
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
HSP90AA1 P07900 1/20 0.57
LMNA P02545 3/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2D6 P10635 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CYP1A1 P04798 1/20 0.54
AHR P35869 1/20 0.54
CYP1B1 Q16678 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
GRIN1 Q05586 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30560952 1.00 HDAC1 (0.62) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL8002124 1.00 HDAC1 (0.62) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL9395898 0.87 MAPT (0.53) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL16586699 0.85 PTGER1 (0.48) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL2328371 0.85 NFKB1 (0.50) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL9652685 0.85 PTGS2 (0.54) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL2744242 0.83 GSR (0.79) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL31553473 0.83 GSR (0.79) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL22596712 0.83 HDAC1 (0.67) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL2744240 0.83 GSR (0.79) HDAC1HDAC8HDAC6GSRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113462278-B Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2024-06-07 CN disclosed
WO-2023107597-A2 BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed
US-6150385-A VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) PHARMACIA & UPJOHN COMPANY (US) 2000-11-21 US disclosed
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed