Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | SDHA | P31040 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002401 | 1.00 | MAOA (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8010967 | 0.84 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8010961 | 0.84 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL14069864 | 0.81 | MAOA (0.53) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6395125 | 0.81 | F10 (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6395123 | 0.81 | F10 (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6397527 | 0.80 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6397521 | 0.80 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7537319 | 0.79 | MAOA (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7537305 | 0.79 | MAOA (0.47) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043266-A | MICROBIOCIDES TREATING GRAM-POSITIVE BACTERIA INFECTIONS AND PERSONS WITH AIDS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |