Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SDHA | P31040 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CALML3 | P27482 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010961 | 1.00 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7030086 | 0.90 | MAOB (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3524539 | 0.85 | F10 (0.41) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3524536 | 0.85 | F10 (0.41) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3524004 | 0.84 | F10 (0.40) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3524011 | 0.84 | F10 (0.40) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8002401 | 0.84 | MAOA (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8002397 | 0.84 | MAOA (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3523454 | 0.84 | F10 (0.39) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3523457 | 0.84 | F10 (0.39) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043266-A | MICROBIOCIDES TREATING GRAM-POSITIVE BACTERIA INFECTIONS AND PERSONS WITH AIDS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |