Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.49 |
| ▸ | CTSS | P25774 | 10/20 | 0.49 |
| ▸ | CTSB | P07858 | 8/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194805 | 0.86 | CTSL (0.67) | CTSLCTSSCTSBCTSK | |
| SCHEMBL12417848 | 0.86 | CTSL (0.45) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2194800 | 0.86 | CTSL (0.67) | CTSLCTSSCTSBCTSK | |
| SCHEMBL28044396 | 0.77 | CTSL (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1198908 | 0.77 | CTSL (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1199773 | 0.77 | CTSL (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2191267 | 0.76 | CTSL (0.69) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1200231 | 0.76 | CTSL (0.69) | CTSLCTSSCTSBCTSK | |
| SCHEMBL14037566 | 0.75 | CTSL (0.52) | CTSLCTSSCTSBCTSK | |
| SCHEMBL12417842 | 0.74 | CTSL (0.48) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123623-A1 | DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY, INC. (US) | 2009-10-08 | — | — | WO | disclosed |