Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.64 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.64 |
| ▸ | TLR4 | O00206 | 3/20 | 0.58 |
| ▸ | TLR2 | O60603 | 3/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499818 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL16499817 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3792351 | 0.81 | TLR4 (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3792354 | 0.81 | TLR4 (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL19710406 | 0.81 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL6185340 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL6185335 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL14907367 | 0.80 | TLR4 (0.50) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL793032 | 0.79 | PRMT1 (0.73) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL27394119 | 0.79 | PRMT1 (0.73) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |