SCHEMBL8002665

SCHEMBL8002665

C#CC(C)(C)OC(N)=O.CCC(C)(C)OC(N)=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.36
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112417 0.86
Ammonia Solution, Strong SCHEMBL28687731 0.84 ELANE (0.42) ELANE
SCHEMBL155686 0.84
Ammonia Solution, Strong SCHEMBL21058276 0.82 ALOX15 (0.40) LMNAHSD17B10ALOX15
Meparfynol Carbamate SCHEMBL1171403 0.75 ALOX15 (0.34) LMNAHSD17B10ALOX15
Meparfynol Carbamate SCHEMBL1171789 0.75 ALOX15 (0.34) LMNAHSD17B10ALOX15
SCHEMBL16013251 0.72 LMNA (0.31) LMNAHSD17B10ALOX15
SCHEMBL31366708 0.71 ELANE (0.34) ELANE
SCHEMBL25468019 0.71 ELANE (0.39) ELANE
SCHEMBL30753033 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732944-A4 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION GEN HOSPITAL CORP (US) 2000-06-07 EP disclosed
EP-0732944-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1996-09-25 EP disclosed
WO-1995011045-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1995-04-27 WO disclosed