Cocarboxylase

Cocarboxylase

SCHEMBL80028

Cc1ncc(C[n+]2csc(CCOP(=O)(O)OP(=O)(O)O)c2C)c(N)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
TKT P29401 7/20 0.86
TDP1 Q9NUW8 1/20 0.85
HSP90AA1 P07900 1/20 0.64
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 1/20 0.52
PPP5C P53041 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cocarboxylase SCHEMBL30192281 1.00 LMNA (1.00) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL28171092 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL28756433 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL27898926 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL23151792 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL23151785 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL28619966 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL21111 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL8923435 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1
Cocarboxylase SCHEMBL991346 0.99 LMNA (0.98) LMNATKTTDP1HSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2243 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012643-A Synthesis method and application of chromone compound catalyzed by benzaldehyde lyase mutant 华东理工大学 2026-05-12 CN claimed
CN-120193031-A Synthesis method and application of amino alcohol compound catalyzed by benzaldehyde lyase mutant 华东理工大学 2025-06-24 CN claimed
WO-2025096781-A1 METHODS AND COMPOSITIONS FOR PROVIDING CUSTOMIZED SKIN REGIMENS VIBRANT HOLDINGS, LLC (US) 2025-05-08 WO claimed
US-20250121095-A1 RECOMBINANT VIRUS EXPRESSING TPK AND USE THEREOF IN TREATMENT OF ALZHEIMER'S DISEASE SHANGHAI RAISING PHARMACEUTICAL CO LTD (CN) 2025-04-17 US claimed
CN-119823882-A Fusarium venenatum with high protein conversion rate and application thereof in improving satiety of hypha protein 江南大学 2025-04-15 CN claimed
CN-115572744-B Biosynthesis method of 1, 4-dihydroxy-2-Ding Tonghua compound 中国科学院天津工业生物技术研究所 2025-04-04 CN claimed
WO-2025059302-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT AND MODULATION OF ACUTE AND CHRONIC SYMPTOMS OF MITOCHONDRIAL DISEASE AND DYSFUNCTION THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2025-03-20 WO claimed
CN-119639839-A Synthesis method of florfenicol and derivatives thereof 上海昱菘生物科技有限公司 2025-03-18 CN claimed
CN-119147681-B Method for detecting water-soluble vitamin metabolites in plants 北京大学现代农业研究院 2025-02-21 CN claimed
WO-2025035032-A2 METHODS AND COMPOSITIONS FOR PROVIDING CUSTOMIZED NUTRITIONAL SUPPLEMENTS VIBRANT HOLDINGS, LLC (US) 2025-02-13 WO claimed
EP-0461731-B1 Synthetic prosthetogens and their use in enzyme linked assays LONDON BIOTECHNOLOGY LTD (GB) 1994-07-13 EP claimed
EP-0156641-B1 ENZYMIC METHOD OF DETECTING ANALYTES AND NOVEL SUBSTRATES THEREFOR London Biotechnology Limited (GB) 1992-06-10 EP claimed
US-5096821-A Stability; genetic engineering BOEHRINGER MANNHEIM GMBH (DE) 1992-03-17 US claimed
EP-0461731-A2 Synthetic prosthetogens and their use in enzyme linked assays LONDON BIOTECHNOLOGY LIMITED (GB) 1991-12-18 EP claimed
US-5057412-A Cleaving pyrimidine rionucleoside diester producing coeneyme for further reaction LONDON BIOTECHNOLOGY LIMITED (GB) 1991-10-15 US claimed
US-4745054-A ENZYME LABELS LONDON BIOTECHNOLOGY LIMITED (GB) 1988-05-17 US claimed
US-4717663-A XANTHOMONAS, CULTURES, AEROBIC, PANTOTHENIC ACID AND/OR THIAMINE (DERIVATIVE) THE NISSHIN OIL MILLS, LTD. (JP) 1988-01-05 US claimed
EP-0156641-A2 Enzymic method of detecting analytes and novel substrates therefor London Biotechnology Limited (GB) 1985-10-02 EP claimed
US-4504496-A Process for improving the flavor and/or the mousseux of sparkling wines and sparkling wines produced according to said process UNDERBERG-HANDELS AG. (CH) 1985-03-12 US claimed
US-4237229-A CONTACTING A PROTEIN, ENZYME, COENZYME, OR ANTIBIOTIC WITH AN ISOCYANATE-CAPPED POLYETHERURETHANE COPOLYMER, SHAPING, AND CURING W. R. GRACE & CO. (US) 1980-12-02 US claimed