Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Cocarboxylase. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.98 |
| ▸ | TKT | P29401 | 7/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.84 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPP5C | P53041 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cocarboxylase SCHEMBL8923435 | 1.00 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL344290 | 0.99 | LMNA (0.96) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL23151784 | 0.99 | LMNA (0.96) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL662896 | 0.99 | LMNA (0.96) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL30192281 | 0.99 | LMNA (1.00) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL80028 | 0.99 | LMNA (1.00) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL478202 | 0.98 | LMNA (0.94) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9766249 | 0.98 | LMNA (0.94) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL23151785 | 0.98 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL28619966 | 0.98 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8913 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747627-A1 | METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS | Matterworks Inc (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122079280-A | 3D printing internal drawing conical solar interface evaporator with directional salt formation function and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-121380249-B | Method for preparing 2' -methoxy-uridine triphosphate | 泰兴合全药业有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122012314-A | Novel intestinal probiotics butyric acid monad and application thereof | 青岛大学 | 2026-05-12 | — | — | CN | claimed |
| WO-2026087508-A1 | HYDROGELS CONTAINING COVALENTLY LINKED COFACTORS AND METHODS FOR PREPARING THE SAME | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2026-04-30 | — | — | WO | claimed |
| EP-4698567-A1 | HYDROGELS CONTAINING COVALENTLY LINKED COFACTORS AND METHODS FOR PREPARING THE SAME | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2026-02-25 | — | — | EP | claimed |
| US-20260022411-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | BIOSYNTIA APS (DK) | 2026-01-22 | — | — | US | claimed |
| US-12509707-B2 | Methods for organic acid production | S&P INGREDIENT DEVELOPMENT, LLC (US) | 2025-12-30 | — | — | US | claimed |
| EP-0133694-A2 | Process for producing neuraminidase and method and reagent for the quantitative determination of a sialic acid-containing substance using neuraminidase | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-03-06 | — | — | EP | claimed |
| US-4503145-A | DIAGNOSIS OF LIVER DISORDERS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-03-05 | — | — | US | claimed |
| EP-0127012-A2 | Antimutagenic agent and a method of reducing mutagenicity | SUNTORY LIMITED (JP) | 1984-12-05 | — | — | EP | claimed |
| EP-0121254-A2 | Process for determining substrate or enzymatic activity | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-10 | — | — | EP | claimed |
| EP-0100413-A1 | Method and preparation for the determination of glutamic-oxalacetic transaminase activity | Roche Diagnostics GmbH (DE) | 1984-02-15 | — | — | EP | claimed |
| EP-0076647-A2 | Culture media for cells originating from the immune system | HANA Biologics Incorporated (US) | 1983-04-13 | — | — | EP | claimed |
| US-4372874-A | Stabilization of hydrolysis prone labile organic reagents in liquid media | MEDICAL ANALYSIS SYSTEMS, INC. | 1983-02-08 | — | — | US | claimed |
| US-4246342-A | BACTERIAL BIOSYNTHESIS, USE IN DETERMINATION OF PYRUVIC ACID | TOYO JOZO KABUSHIKI KAISHA (JP) | 1981-01-20 | — | — | US | claimed |
| US-4237229-A | CONTACTING A PROTEIN, ENZYME, COENZYME, OR ANTIBIOTIC WITH AN ISOCYANATE-CAPPED POLYETHERURETHANE COPOLYMER, SHAPING, AND CURING | W. R. GRACE & CO. (US) | 1980-12-02 | — | — | US | claimed |
| US-4006223-A | Drug composition intended for the treatment of acute, lethal and chronic radiation disease | SPITALUL CLINIC FILANTROPIA BUCURESTI (RU) | 1977-02-01 | — | — | US | claimed |