Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 10/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304302 | 0.92 | FAAH (0.44) | LMNATDP1L3MBTL1FAAHKDM4C | |
| SCHEMBL1302719 | 0.73 | FAAH (0.50) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL8006548 | 0.72 | MAOA (0.46) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL1304298 | 0.72 | FAAH (0.67) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL12106886 | 0.70 | FAAH (0.48) | LMNATDP1L3MBTL1FAAHKDM4C | |
| SCHEMBL8005254 | 0.70 | FAAH (0.55) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL8006327 | 0.69 | GAA (0.52) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL1303791 | 0.68 | MAOA (0.50) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL12106073 | 0.68 | FAAH (0.46) | LMNATDP1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL1303162 | 0.67 | FAAH (0.45) | LMNATDP1L3MBTL1FAAHKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152025-A1 | IMIDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2009-12-17 | — | — | WO | disclosed |