Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 4/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800758 | 1.00 | P2RY14 (0.38) | P2RY14TDP1DUTP2RY2P2RY12 | |
| SCHEMBL780531 | 0.92 | P2RY14 (0.38) | P2RY14TDP1DUTP2RY2TYMP | |
| SCHEMBL781934 | 0.92 | P2RY14 (0.38) | P2RY14TDP1DUTP2RY2TYMP | |
| SCHEMBL21475705 | 0.90 | P2RY14 (0.43) | P2RY14P2RY2TYMPP2RY6SLC28A1 | |
| SCHEMBL21461830 | 0.81 | P2RY14 (0.41) | P2RY14P2RY2TYMPP2RY6SLC28A1 | |
| SCHEMBL21475782 | 0.81 | TDP1 (0.42) | P2RY14TDP1P2RY2P2RY12P2RY6 | |
| SCHEMBL800303 | 0.80 | TYMP (0.34) | P2RY14P2RY2TYMPP2RY6 | |
| SCHEMBL800718 | 0.80 | TYMP (0.34) | P2RY14P2RY2TYMPP2RY6 | |
| SCHEMBL781654 | 0.80 | SLC28A1 (0.47) | P2RY14DUTP2RY2P2RY12TYMP | |
| SCHEMBL781655 | 0.80 | SLC28A1 (0.47) | P2RY14DUTP2RY2P2RY12TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070411-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070411-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | PNP, NTPCR, NUDT1 | P2RY14 93/4885TDP1 403/4885DUT 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.