Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyramine SCHEMBL19031740 | 0.83 | TAAR1 (0.62) | TAAR1ALDH1A1KDM4EADRA2ASLC6A2 | |
| 4-Aminophenol SCHEMBL9806770 | 0.83 | IDO1 (0.57) | ALDH1A1KDM4ETDP1BLMKMT2A | |
| Putrescine SCHEMBL7991111 | 0.79 | IDO1 (0.57) | TAAR1ALDH1A1KDM4ETDP1BLM | |
| SCHEMBL485855 | 0.78 | IDO1 (0.73) | ALDH1A1KDM4ETDP1BLMKMT2A | |
| SCHEMBL29393764 | 0.78 | IDO1 (0.73) | ALDH1A1KDM4ETDP1BLMKMT2A | |
| SCHEMBL8371459 | 0.78 | IDO1 (0.73) | ALDH1A1KDM4ETDP1BLMKMT2A | |
| SCHEMBL8006509 | 0.78 | IDO1 (0.73) | ALDH1A1KDM4ETDP1BLMKMT2A | |
| SCHEMBL29702452 | 0.78 | IDO1 (0.73) | ALDH1A1KDM4ETDP1BLMKMT2A | |
| Tyramine SCHEMBL8006483 | 0.78 | TAAR1 (0.55) | TAAR1ALDH1A1KDM4EADRA2ASLC6A2 | |
| Tyramine SCHEMBL7991027 | 0.78 | ALDH1A1 (0.55) | TAAR1ALDH1A1KDM4EADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |