Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyramine SCHEMBL8006483 | 0.88 | TAAR1 (0.55) | ALDH1A1TAAR1KDM4EL3MBTL1HTR1A | |
| Hydroquinone SCHEMBL9776726 | 0.85 | F2 (0.56) | ALDH1A1KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL8001257 | 0.83 | F2 (0.58) | ALDH1A1KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL29792935 | 0.83 | F2 (0.58) | ALDH1A1KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL208278 | 0.83 | F2 (0.58) | ALDH1A1KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL29394466 | 0.82 | F2 (0.56) | ALDH1A1KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL29164286 | 0.82 | F2 (0.56) | ALDH1A1KDM4EL3MBTL1TDP1KMT2A | |
| Tyramine SCHEMBL8003043 | 0.78 | TAAR1 (0.58) | ALDH1A1TAAR1KDM4EL3MBTL1HTR1A | |
| SCHEMBL7103988 | 0.76 | MTNR1A (0.57) | TAAR1HTR1AHTR3ADRD2DRD1 | |
| 3-Aminophenol SCHEMBL7991144 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |