SCHEMBL8003429

SCHEMBL8003429

CCC[Si]1(c2ccccc2)CCC(C2CCCCC2=O)CC1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MT-CO2 P00403 4/20 0.38
ALOX5 P09917 4/20 0.38
MCL1 Q07820 1/20 0.35
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
HPGD P15428 1/20 0.33
SLC18A3 Q16572 1/20 0.32
CA1 P00915 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015163 0.91 MT-CO2 (0.36) MT-CO2ALOX5MCL1MAPTKDM4E
SCHEMBL8017954 0.81 L3MBTL1 (0.33)
SCHEMBL7756311 0.80
SCHEMBL8015518 0.79 MT-CO2 (0.43) MT-CO2ALOX5MCL1MAPTKDM4E
SCHEMBL8026441 0.74
SCHEMBL8448145 0.74
SCHEMBL8021312 0.73 MEN1 (0.32)
SCHEMBL8917046 0.72 KCNA3 (0.32)
SCHEMBL8917063 0.72 NPC1 (0.37) ALDH1A1
SCHEMBL7758047 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692485-B1 Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound SHINETSU CHEMICAL CO (JP) 2000-01-05 EP disclosed
US-5519156-A Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-21 US disclosed
EP-0692485-A1 Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound Shin-Etsu Chemical Co., Ltd. (JP) 1996-01-17 EP disclosed