Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 15/20 | 0.55 |
| ▸ | MMP1 | P03956 | 4/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013077 | 0.91 | BMP1 (0.55) | BMP1MMP1MMP8POLBTSHR | |
| SCHEMBL8012495 | 0.89 | BMP1 (0.61) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8012367 | 0.88 | BMP1 (0.52) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8015014 | 0.88 | BMP1 (0.54) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8014652 | 0.87 | BMP1 (0.52) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8003538 | 0.87 | BMP1 (0.51) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8012716 | 0.87 | BMP1 (0.58) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8014668 | 0.85 | MMP2 (0.57) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8016090 | 0.85 | BMP1 (0.49) | BMP1MMP1MMP8MMP9MMP13 | |
| SCHEMBL8012383 | 0.85 | BMP1 (0.53) | BMP1MMP1MMP8MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |