Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA7 | P43166 | 3/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18652188 | 0.91 | ESR1 (0.62) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL23484566 | 0.89 | MAPK1 (0.64) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL18652233 | 0.89 | MAPK1 (0.64) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL24305987 | 0.85 | MAPK1 (0.60) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL4648142 | 0.85 | SERPINE1 (0.56) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL1348236 | 0.84 | MAPK1 (0.68) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL8003820 | 0.84 | MAPK1 (0.58) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL3793737 | 0.83 | LMNA (0.65) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL7534902 | 0.82 | SERPINE1 (0.53) | MAPK1ESR1CA12CA1CA2 | |
| SCHEMBL204567 | 0.82 | MAPK1 (0.71) | MAPK1SERPINE1TSHRALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566682-B2 | 1,2-bis(3-methylphenoxy)ethane composition and thermal recording media made by using the same | SANKO CO., LTD (JP) | 2009-07-28 | — | — | US | claimed |
| US-20070111887-A1 | 1,2-Bis(3-methylphenoxy)ethane composition and thermal recording media made by using the same | SANKO CO., LTD. (JP) | 2007-05-17 | — | — | US | claimed |
| EP-1595714-B1 | 1,2-BIS(3-METHYLPHENOXY)ETHANE COMPOSITION AND THERMAL RECORDING MEDIA MADE BY USING THE SAME | SANKO CO LTD (JP) | 2007-04-11 | — | — | EP | claimed |
| EP-1595714-A1 | 1,2-BIS(3-METHYLPHENOXY)ETHANE COMPOSITION AND THERMAL RECORDING MEDIA MADE BY USING THE SAME | Sanko Co., Ltd. (JP) | 2005-11-16 | — | — | EP | claimed |
| EP-1396347-A2 | Heat-sensitive recording material and production method thereof | Sanko Co., Ltd. (JP) | 2004-03-10 | — | — | EP | claimed |
| US-20040043902-A1 | Heat-sensitive recording material and production method thereof | SANKO CO., LTD. (JP) | 2004-03-04 | — | — | US | claimed |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |
| US-20230018132-A1 | REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME | RISO TECHNOLOGIES CORPORATION (JP) | 2023-01-19 | — | — | US | disclosed |
| EP-1396347-A2 | Heat-sensitive recording material and production method thereof | Sanko Co., Ltd. (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-1396347-A2 | Heat-sensitive recording material and production method thereof | Sanko Co., Ltd. (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-20040043902-A1 | Heat-sensitive recording material and production method thereof | SANKO CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| US-20040043902-A1 | Heat-sensitive recording material and production method thereof | SANKO CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-0821715-A1 | THERMOSET COATING COMPOSITIONS HAVING IMPROVED HARDNESS | EXXON CHEMICAL PATENTS INC. (US) | 1998-02-04 | — | — | EP | disclosed |
| US-5681906-A | CROSSLINKABLE COATING | EXXON CHEMICAL PATENTS INC. (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996033245-A1 | THERMOSET COATING COMPOSITIONS HAVING IMPROVED HARDNESS | EXXON CHEMICAL PATENTS INC. (US) | 1996-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | MAPK1 235/4885ESR1 4366/4885CA12 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.