Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 12/20 | 0.54 |
| ▸ | MMP13 | P45452 | 4/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMP15 | P51511 | 1/20 | 0.42 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413557 | 0.90 | MMP1 (0.50) | MMP1ADAM17MMP13MMP9ADAMTS4 | |
| SCHEMBL7507039 | 0.88 | MMP1 (0.48) | MMP1ADAM17MMP13MMP9SPHK1 | |
| SCHEMBL8003903 | 0.87 | MMP1 (0.57) | MMP1ADAM17MMP13MMP9ADAMTS4 | |
| SCHEMBL19066004 | 0.83 | MMP1 (0.50) | MMP1ADAM17MMP13MMP9ADAMTS4 | |
| SCHEMBL7511310 | 0.80 | MMP1 (0.50) | MMP1ADAM17MMP13MMP9MMP2 | |
| SCHEMBL7594294 | 0.80 | MMP1 (0.55) | MMP1ADAM17MMP13MMP9MMP2 | |
| SCHEMBL7512525 | 0.79 | MMP1 (0.53) | MMP1ADAM17MMP13MMP9MMP2 | |
| SCHEMBL7625228 | 0.78 | MMP1 (0.44) | MMP1ADAM17MMP13MMP9MMP2 | |
| SCHEMBL7506020 | 0.78 | S1PR5 (0.53) | MMP1ADAM17MMP13MMP9SPHK1 | |
| SCHEMBL7622790 | 0.78 | MMP1 (0.53) | MMP1ADAM17MMP13MMP9ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |