Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 12/20 | 0.57 |
| ▸ | MMP13 | P45452 | 5/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407350 | 0.89 | MMP1 (0.48) | MMP1ADAM17MMP13ADAMTS4MMP9 | |
| SCHEMBL8003950 | 0.87 | MMP1 (0.54) | MMP1ADAM17MMP13ADAMTS4MMP9 | |
| SCHEMBL7412782 | 0.86 | MAPT (0.51) | MMP1ADAM17PKM | |
| SCHEMBL7650964 | 0.77 | MMP1 (0.51) | MMP1ADAM17MMP13MMP9MMP2 | |
| SCHEMBL7413557 | 0.76 | MMP1 (0.50) | MMP1ADAM17MMP13ADAMTS4MMP9 | |
| SCHEMBL19066004 | 0.76 | MMP1 (0.50) | MMP1ADAM17MMP13ADAMTS4MMP9 | |
| SCHEMBL7513095 | 0.74 | KMT2A (0.47) | MMP1ADAM17MMP13MMP9PKM | |
| SCHEMBL7507039 | 0.74 | MMP1 (0.48) | MMP1ADAM17MMP13MMP9PKM | |
| SCHEMBL7628372 | 0.74 | MMP1 (0.49) | MMP1ADAM17MMP13MMP9MMP2 | |
| SCHEMBL7594294 | 0.73 | MMP1 (0.55) | MMP1ADAM17MMP13MMP9BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |