Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372397 | 0.84 | CYP3A4 (0.37) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL577111 | 0.83 | RECQL (0.42) | POLBKMT2AMEN1ALDH1A1RECQL | |
| SCHEMBL8000890 | 0.81 | POLB (0.36) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL20355369 | 0.81 | PIK3CA (0.37) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8007192 | 0.81 | GSK3A (0.40) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8004061 | 0.81 | POLB (0.35) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL3220307 | 0.77 | NOS3 (0.48) | KDM4EALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL15339519 | 0.76 | RECQL (0.38) | POLBKMT2AMEN1ALDH1A1NOS3 | |
| SCHEMBL1674658 | 0.76 | PIK3CA (0.37) | POLBALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL31345511 | 0.76 | PIK3CA (0.37) | POLBALDH1A1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009104729-A1 | AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | 大日本住友製薬株式会社 (JP) | 2009-08-27 | — | — | WO | disclosed |