SCHEMBL8004081

SCHEMBL8004081

CCC(C)(c1ccc(Oc2ccc(N)cc2)cc1)c1cc(C)c(Oc2ccc(N)c(C)c2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
ALDH1A1 P00352 6/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 1/20 0.44
ESR1 P03372 2/20 0.39
AR P10275 1/20 0.39
ESR2 Q92731 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
TEAD4 Q15561 1/20 0.37
POLB P06746 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
NLRP1 Q9C000 1/20 0.36
NOD2 Q9HC29 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9177309 0.89 MAPT (0.49) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL2895331 0.88 MAPT (0.54) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL8004085 0.82 MAPT (0.49) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL1857763 0.81 MAPT (0.73) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL10350063 0.78 ALDH1A1 (0.61) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL7185516 0.78 ALDH1A1 (0.61) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL31457310 0.78 ALDH1A1 (0.61) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL2894196 0.77 MAPT (0.51) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL22580584 0.76 NPC1 (0.45) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL8776942 0.75 MAPT (0.51) MAPTRAB9ANPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6087470-A Preparation of soluble polyamide, polyimide and poly(amide-imide) NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) 2000-07-11 US claimed
US-6087470-A Preparation of soluble polyamide, polyimide and poly(amide-imide) NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) 2000-07-11 US disclosed