SCHEMBL1857763

SCHEMBL1857763

CCC(C)(c1ccc(Oc2ccc(N)cc2)cc1)c1ccc(Oc2ccc(N)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.73
RAB9A P51151 4/20 0.73
NPC1 O15118 3/20 0.73
ALDH1A1 P00352 7/20 0.66
MAPK1 P28482 2/20 0.66
HPGD P15428 1/20 0.66
TDP1 Q9NUW8 5/20 0.54
TSHR P16473 2/20 0.54
CYP3A4 P08684 2/20 0.54
TEAD4 Q15561 1/20 0.50
POLB P06746 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
MAOA P21397 2/20 0.47
MAOB P27338 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MITF O75030 1/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
NLRP1 Q9C000 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7045232 0.88 MAPT (0.53) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL22289386 0.86 ALDH1A1 (0.68) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL5177727 0.85 MAPT (0.64) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL15054796 0.85 MAPT (1.00) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL29947925 0.83 MAOB (0.56) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL308673 0.83 MAOB (0.56) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL7607195 0.82 MAPT (0.70) MAPTRAB9ANPC1ALDH1A1MAPK1
Propane SCHEMBL28248416 0.82 MAPT (0.70) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL25969481 0.82 LTA4H (0.53) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL20133387 0.82 MAPT (0.50) MAPTRAB9ANPC1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100459-A Preparation method of fluororesin-containing modified polyimide film 无锡顺意锐新材料研究有限公司 2020-05-05 CN claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
US-12479194-B2 Laminate TOYOBO CO., LTD. (JP) 2025-11-25 US disclosed
US-12472732-B2 Laminate, method for manufacturing laminate, and method for manufacturing flexible electronic device TOYOBO CO., LTD. (JP) 2025-11-18 US disclosed
US-12391813-B2 Layered body including inorganic substrate and polyamic acid cured product TOYOBO CO., LTD. (JP) 2025-08-19 US disclosed
WO-2025047667-A1 SHEET MATERIAL AND METHOD FOR PRODUCING SHEET MATERIAL 東洋紡株式会社 2025-03-06 WO disclosed
US-20250019508-A1 LAYERED BODY INCLUDING INORGANIC SUBSTRATE AND POLYAMIC ACID CURED PRODUCT TOYOBO CO., LTD. (JP) 2025-01-16 US disclosed
WO-2024262187-A1 RESIN FILM, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, AND METHOD FOR PRODUCING RESIN FILM 東洋紡株式会社 2024-12-26 WO disclosed
US-12172409-B2 Laminate of inorganic substrate/polymer film layer with attached protective film, laminate stack, laminate storage method, and laminate transport method TOYOBO CO., LTD. (JP) 2024-12-24 US disclosed
US-20240395547-A1 SEMICONDUCTOR APPARATUS AND METHOD FOR MANUFACTURING SEMICONDUCTOR APPARATUS UNIVERSITY OF TSUKUBA (JP) 2024-11-28 US disclosed
EP-0336536-A2 Organic-solvent soluble polyimide and production thereof Hitachi Chemical Co., Ltd. (JP) 1989-10-11 EP disclosed
EP-0333406-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-20 EP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0297808-A1 Polyimide and high-temperature adhesive thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-01-04 EP disclosed
US-4791157-A REACTING TRIMELLITIC ACID WITH AROMATIC DIAMINE WITH ETHER GROUPS HITACHI CHEMICAL CO. (JP) 1988-12-13 US disclosed
EP-0294129-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-12-07 EP disclosed
EP-0294144-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-12-07 EP disclosed
US-4758875-A Resin encapsulated semiconductor device HITACHI, LTD. (JP) 1988-07-19 US disclosed
EP-0269319-A2 Polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-01 EP disclosed