SCHEMBL80043

SCHEMBL80043

N#Cc1cccc(I)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732358 1.00
SCHEMBL1009061 0.98 ENPP2 (0.47)
SCHEMBL24648525 0.87 CLK4 (0.53)
SCHEMBL920249 0.82 PDE4A (0.47)
Trifluoroacetic Acid SCHEMBL30533120 0.82 PDK1 (0.43)
SCHEMBL2817154 0.81 TSHR (0.61)
SCHEMBL9289 0.81 TSHR (0.61)
Water SCHEMBL28137572 0.81 TSHR (0.61)
Hydrochloric Acid SCHEMBL19327577 0.78 TSHR (0.58)
Fluoride SCHEMBL28362409 0.78 TSHR (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024530-B Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof 合肥工业大学 2023-07-18 CN claimed
CN-112939829-B Synthetic method of aryl trifluoromethyl thioether 武汉药明康德新药开发有限公司 2023-02-21 CN claimed
WO-2023283974-A1 DEUTERATED AMMONIA PREPARATION METHOD AND DEUTERATION REACTION INVOLVING SAME AS DEUTERIUM SOURCE 苏州大学 2023-01-19 WO claimed
CN-114394891-A Compound prepared by catalyzing chalcone with monovalent iodine reagent, and preparation method and application thereof 化学与精细化工广东省实验室 2022-04-26 CN claimed
CN-113526526-A Preparation method of deuterated ammonia and deuterated reaction taking deuterated ammonia as deuterium source to participate 苏州大学 2021-10-22 CN claimed
CN-113024530-A Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof 合肥工业大学 2021-06-25 CN claimed
CN-112939829-A Synthetic method of aryl trifluoromethyl thioether 武汉药明康德新药开发有限公司 2021-06-11 CN claimed
CN-109320583-A A kind of dehydroabietic acid benzimidazole thioether class Hete rocyclic derivatives with anti-tumor activity and its preparation method and application 南京林业大学 2019-02-12 CN claimed
CN-102149732-B Catalyst for living radical polymerization UNIV KYOTO 2014-07-09 CN claimed
US-8575285-B2 Catalyst for living radical polymerization KYOTO UNIVERSITY (JP) 2013-11-05 US claimed
US-20110275775-A1 CATALYST FOR LIVING RADICAL POLYMERIZATION KYOTO UNIVERSITY (JP) 2011-11-10 US claimed
CN-102149732-A Catalyst for living radical polymerization UNIV KYOTO 2011-08-10 CN claimed
EP-2325213-A1 CATALYST FOR LIVING RADICAL POLYMERIZATION Kyoto University (JP) 2011-05-25 EP claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
EP-4126835-B1 INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR JANSSEN PHARMACEUTICA NV (BE) 2026-02-18 EP disclosed
EP-4685143-A1 DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF Vivozon,Inc. (KR) 2026-01-28 EP disclosed
WO-1988007509-A1 PROCESS FOR PREPARING IODINATED SUBSTITUTED AROMATIC COMPOUNDS EASTMAN KODAK COMPANY (US) 1988-10-06 WO disclosed
US-4579848-A ANTIASTHMA AGENTS AMERICAN CYANAMID COMPANY (US) 1986-04-01 US disclosed
EP-0132851-A1 5-Substituted(1,2,4)triazolo(1,5-c)pyrimidin-2-amines AMERICAN CYANAMID COMPANY (US) 1985-02-13 EP disclosed