Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508163 | 1.00 | KMT2A (0.35) | KMT2ARENTSHRGSK3BKCNH2 | |
| SCHEMBL4510550 | 0.97 | KMT2A (0.38) | KMT2ARENTSHRALDH2 | |
| SCHEMBL8001001 | 0.91 | KMT2A (0.33) | KMT2ARENTSHR | |
| SCHEMBL7992016 | 0.91 | KMT2A (0.33) | KMT2ARENTSHR | |
| SCHEMBL4492525 | 0.91 | REN (0.33) | KMT2ARENTSHRMAPTTHRB | |
| SCHEMBL4492527 | 0.91 | REN (0.33) | KMT2ARENTSHRMAPTTHRB | |
| SCHEMBL4502016 | 0.91 | REN (0.34) | KMT2ARENTSHRKCNH2MAPT | |
| SCHEMBL4506756 | 0.90 | PKM (0.34) | KMT2ARENTSHRMAPTTHRB | |
| SCHEMBL4509437 | 0.90 | REN (0.31) | KMT2AREN | |
| SCHEMBL4495105 | 0.90 | REN (0.31) | KMT2AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106599-A2 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| WO-2007141318-A1 | 2,5-DISUBSTITUTED PIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-12-13 | — | — | WO | disclosed |