Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074569 | 0.86 | NPC1 (0.47) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL8076775 | 0.86 | NPC1 (0.47) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL7997204 | 0.86 | NPC1 (0.57) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL8001310 | 0.85 | NPC1 (0.46) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL7999762 | 0.85 | NPC1 (0.56) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL8004179 | 0.85 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2TYMSLMNA | |
| SCHEMBL8081180 | 0.84 | NPC1 (0.46) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL8004045 | 0.84 | NPC1 (0.45) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL8004668 | 0.83 | NPC1 (0.54) | NPC1MEN1KMT2AKDM4ERGS12 | |
| SCHEMBL7999324 | 0.83 | ALDH1A1 (0.38) | NPC1MEN1KMT2AKDM4ERGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |