Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962386 | 0.87 | FAAH (0.48) | FAAHKCNH2ELOVL1ALDH1A1CYP1A2 | |
| SCHEMBL12552087 | 0.84 | FAAH (0.61) | FAAHKCNH2ELOVL1ALDH1A1CYP1A2 | |
| SCHEMBL1962427 | 0.83 | FAAH (0.47) | FAAHKCNH2ELOVL1ALDH1A1CYP1A2 | |
| SCHEMBL1535397 | 0.82 | FAAH (0.64) | FAAHKCNH2ELOVL1ALDH1A1CYP1A2 | |
| SCHEMBL1961073 | 0.82 | FAAH (0.50) | FAAHKCNH2ELOVL1ALDH1A1CYP1A2 | |
| SCHEMBL1959648 | 0.78 | FAAH (0.50) | FAAHKCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1963411 | 0.78 | FAAH (0.49) | FAAHKCNH2ELOVL1RXFP1ICAM1 | |
| SCHEMBL1961329 | 0.77 | FAAH (0.49) | FAAHKCNH2ELOVL1CYP2C9RXFP1 | |
| SCHEMBL8002415 | 0.76 | FAAH (0.42) | FAAHKCNH2ELOVL1PTGS2ICAM1 | |
| SCHEMBL12551943 | 0.76 | FAAH (0.54) | FAAHKCNH2ELOVL1CYP3A4ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151991-A1 | PYRAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2009-12-17 | — | — | WO | disclosed |