SCHEMBL8004680

SCHEMBL8004680

CCOC(F)=C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
HDAC4 P56524 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9587400 0.80
SCHEMBL8419481 0.76
SCHEMBL21925295 0.74
SCHEMBL10716350 0.74
SCHEMBL5028721 0.71
SCHEMBL21925270 0.70
SCHEMBL8006620 0.69
SCHEMBL154401 0.69
SCHEMBL13516087 0.69 ALDH1A1 (0.38) ALDH1A1HDAC4HDAC6HDAC3HDAC1
SCHEMBL9587537 0.69 LMNA (0.30) HDAC4HDAC6HDAC3HDAC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051381-A1 PROCESS FOR PREPARING HYDROFLUOROETHERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-11-15 EP disclosed
US-6023002-A REACTION OF A FLUORINATED ALKOXIDE WITH AN ALKYL FLUOROVINYLALKYL ETHER, THE ALKYL FLUOROVINYLALKYL ETHER HAVING ALPHA-BETA CARBON-CARBON UNSATURATION RELATIVE TO THE ETHER OXYGEN 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-02-08 US disclosed
EP-0670294-B1 Process for making hexafluoropropane and perfluoropropane MINNESOTA MINING & MFG (US) 1999-09-22 EP disclosed
WO-1999037598-A1 PROCESS FOR PREPARING HYDROFLUOROETHERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-07-29 WO disclosed
EP-0753085-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-15 EP disclosed
US-5573654-A Process for making hexafluoropropane and perfluoropropane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-12 US disclosed
WO-1995026429-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-05 WO disclosed
EP-0670294-A2 Process for making hexafluoropropane and perfluoropropane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-06 EP disclosed
US-3960758-A SULFUR-CONTAINING PHENOL BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed
US-3935200-A HERBICIDE BASF AKTIENGESELLSCHAFT (DT) 1976-01-27 US disclosed