Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533542 | 0.80 | L3MBTL1 (0.41) | KDM4EALDH1A1L3MBTL1POLBNPC1 | |
| SCHEMBL2530786 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1POLBNPC1 | |
| SCHEMBL11993082 | 0.69 | NPC1 (0.46) | KDM4EALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL2529456 | 0.69 | ICAM1 (0.37) | KDM4EALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL19622235 | 0.69 | ICAM1 (0.37) | KDM4EALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL15361109 | 0.67 | KDM4C (0.47) | KDM4EALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL29901049 | 0.66 | MEN1 (0.36) | ALDH1A1L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL2529332 | 0.65 | ICAM1 (0.35) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11993081 | 0.65 | NPC1 (0.42) | ALDH1A1L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL22110809 | 0.65 | KDM4C (0.40) | ALDH1A1L3MBTL1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |