Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999242 | 0.92 | RORA (0.32) | KDM4EALDH1A1 | |
| SCHEMBL8000839 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL7988319 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL7999452 | 0.90 | TTR (0.36) | — | |
| SCHEMBL8004464 | 0.85 | CYP1A2 (0.38) | GAAMAPT | |
| SCHEMBL8001062 | 0.85 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAMAPTGFER | |
| SCHEMBL7997700 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1GAAMAPTGFER | |
| SCHEMBL7998916 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1GAAMAPTGFER | |
| SCHEMBL7988376 | 0.83 | GSK3B (0.35) | KDM4EALDH1A1GAAMAPTGFER | |
| SCHEMBL7999026 | 0.83 | GSK3B (0.35) | KDM4EALDH1A1GAAMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |