Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RORA | P35398 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996990 | 0.92 | NPC1 (0.39) | NPC1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL8004493 | 0.90 | NPC1 (0.52) | NPC1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7999322 | 0.86 | ALDH1A1 (0.38) | NPC1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7997667 | 0.83 | NPC1 (0.46) | NPC1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7997663 | 0.83 | NPC1 (0.46) | NPC1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7989437 | 0.83 | ADRA2A (0.44) | KDM4EHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7997313 | 0.82 | ALDH1A1 (0.41) | NPC1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL8004176 | 0.82 | MEN1 (0.47) | NPC1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7988429 | 0.82 | TYMS (0.40) | KDM4EHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8001122 | 0.82 | TYMS (0.40) | KDM4EHPGDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |